Nessus

Nessus has been around for a little more than a little while now and has gone from free to almost free to it's gonna cost ya.
I'm not really sure regarding the newest updates as I haven't used it since it lost it's freedom, but I will say it has plugins for everything under the sun!
It is mainly used for network and server scanning and has the ability to test and create a client/server connection between yourself and the host you're testing with.