Tenable Nessus
Nessus was a popular free and open source vulnerability scanner until they closed the source code in 2005 and removed the free "registered feed" version in 2008. A limited “Home Feed” is still available, though it is only licensed for home network use. Some people avoid paying by violating the “Home Feed” license, or by avoiding feeds entirely and using just the plugins included with each release. But for most users, the cost has increased from free to $1200/year. Despite this, Nessus is still the best UNIX vulnerability scanner available and among the best to run on Windows. Nessus is constantly updated, with more than 20,000 plugins. Key features include remote and local (authenticated) security checks, a client/server architecture with a GTK graphical interface, and an embedded scripting language for writing your own plugins or understanding the existing ones.